Fix carotid body classification: move from cardiovascular to peripheral nervous system #3594
Conversation
This file contains hidden or bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
…al nervous system - Changed part_of relationship from UBERON:0001530 (common carotid artery plus branches) to UBERON:0000010 (peripheral nervous system) - Added PMID:32965908 reference supporting anatomical classification - Carotid body is adjacent to, not part of, the carotid artery bifurcation - Added required metadata: dcterms-date and term_tracker_item for issue #3591 Fixes #3591 @dragon-ai-agent Co-Authored-By: Claude <noreply@anthropic.com>
Contributor
|
This PR has not seen any activity in the past month; if nobody comments or reviews it in the next week, the PR creator will be allowed to proceed with merging without explicit approval, should they wish to do so. |
Contributor
|
Looks like duplicate with #3595 Close? |
Contributor
|
This PR has not seen any activity in the past month; if nobody comments or reviews it in the next week, the PR creator will be allowed to proceed with merging without explicit approval, should they wish to do so. |
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Add this suggestion to a batch that can be applied as a single commit.
This suggestion is invalid because no changes were made to the code.
Suggestions cannot be applied while the pull request is closed.
Suggestions cannot be applied while viewing a subset of changes.
Only one suggestion per line can be applied in a batch.
Add this suggestion to a batch that can be applied as a single commit.
Applying suggestions on deleted lines is not supported.
You must change the existing code in this line in order to create a valid suggestion.
Outdated suggestions cannot be applied.
This suggestion has been applied or marked resolved.
Suggestions cannot be applied from pending reviews.
Suggestions cannot be applied on multi-line comments.
Suggestions cannot be applied while the pull request is queued to merge.
Suggestion cannot be applied right now. Please check back later.
Summary
This PR fixes the anatomical classification of the carotid body (UBERON:0001629) by changing its system membership from cardiovascular to peripheral nervous system, as requested in issue #3591.
Changes Made:
part_ofrelationship fromUBERON:0001530(common carotid artery plus branches) toUBERON:0000010(peripheral nervous system)PMID:32965908which provides evidence supporting this anatomical classificationdcterms-date,term_tracker_itemfor issue tracking, andcreated_byattributionRationale:
According to the current definition and evidence from PMID:32965908, the carotid body is "a sensory organ in the peripheral nervous system located in the adventitia of the bifurcation of the common carotid artery". While the structure is anatomically adjacent to the carotid artery bifurcation, it is functionally and developmentally not part of the cardiovascular system - it belongs to the peripheral nervous system as a chemoreceptive sensory organ.
Validation:
is_arelationship toUBERON:0034979(nonchromaffin paraganglion)overlapsannotations for carotid arteriesFixes #3591
@dragon-ai-agent