Add terms for inner & outer cortex of thyroid cartilage #3536
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Added two new terms as requested in issue #3535: - UBERON:7770001 inner cortex of thyroid cartilage - UBERON:7770002 outer cortex of thyroid cartilage Both terms are part_of thyroid cartilage (UBERON:0001738) @dragon-ai-agent
dosumis
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@dragon-ai-agent please update the definitions. They are almost perfect, but it would be better if each term definition explicitly references the other in comparative statements. e.g. "The inner region of the thyroid cartilage characterized by less mineralized tissue" --> "The inner region of the thyroid cartilage characterized by less mineralized tissue than the outer region
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Having looked more carefully at the sources, I am not convinced they support the assertions. I am researching further. |
aleixpuigb
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Please, see inline comments. I couldn't find the majority of information from the definitions in the provided references
| [Term] | ||
| id: UBERON:7770001 | ||
| name: inner cortex of thyroid cartilage | ||
| def: "The inner region of the thyroid cartilage characterized by less mineralized tissue, with a higher proportion of chondrocytes and proteoglycans providing flexibility. It directly supports the vocal ligaments and thyroarytenoid muscles." [https://geiselmed.dartmouth.edu/radiology/wp-content/uploads/sites/47/2019/04/Pitfalls-Staging-Laryngeal-SCCa-2013-Baugnon.pdf, https://www.kenhub.com/en/library/anatomy/thyroid-cartilage, https://www.ncbi.nlm.nih.gov/books/NBK538202/] |
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It would be advisable to use the PMID for:
| [Term] | ||
| id: UBERON:7770001 | ||
| name: inner cortex of thyroid cartilage | ||
| def: "The inner region of the thyroid cartilage characterized by less mineralized tissue, with a higher proportion of chondrocytes and proteoglycans providing flexibility. It directly supports the vocal ligaments and thyroarytenoid muscles." [https://geiselmed.dartmouth.edu/radiology/wp-content/uploads/sites/47/2019/04/Pitfalls-Staging-Laryngeal-SCCa-2013-Baugnon.pdf, https://www.kenhub.com/en/library/anatomy/thyroid-cartilage, https://www.ncbi.nlm.nih.gov/books/NBK538202/] |
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From the kenhub page referenced:
The internal surface of the thyroid cartilage is covered by a mucous membrane. The angle serves as the attachment point for several laryngeal ligaments and muscles such as the thyroepiglottic, vestibular and vocal ligaments as well as the thyroarytenoid, thyroepiglottic and vocalis muscles.
- We can add the exact synonym 'internal surface of thyroid cartilage' (also in PMID:30855790)
- It lists more muscles and ligaments that are suported by this structure.
| [Term] | ||
| id: UBERON:7770001 | ||
| name: inner cortex of thyroid cartilage | ||
| def: "The inner region of the thyroid cartilage characterized by less mineralized tissue, with a higher proportion of chondrocytes and proteoglycans providing flexibility. It directly supports the vocal ligaments and thyroarytenoid muscles." [https://geiselmed.dartmouth.edu/radiology/wp-content/uploads/sites/47/2019/04/Pitfalls-Staging-Laryngeal-SCCa-2013-Baugnon.pdf, https://www.kenhub.com/en/library/anatomy/thyroid-cartilage, https://www.ncbi.nlm.nih.gov/books/NBK538202/] |
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I can't see all the information in the references:
... characterized by less mineralized tissue, with a higher proportion of chondrocytes and proteoglycans providing flexibility
| [Term] | ||
| id: UBERON:7770002 | ||
| name: outer cortex of thyroid cartilage | ||
| def: "The outer region of the thyroid cartilage containing denser hyaline cartilage with a higher collagen matrix density, providing structural rigidity. It serves as the attachment site for extrinsic muscles (e.g., sternothyroid, thyrohyoid) via the oblique line on the external surface." [https://geiselmed.dartmouth.edu/radiology/wp-content/uploads/sites/47/2019/04/Pitfalls-Staging-Laryngeal-SCCa-2013-Baugnon.pdf, https://www.kenhub.com/en/library/anatomy/thyroid-cartilage, https://teachmeanatomy.info/neck/viscera/larynx/laryngealcartilages/] |
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This page doesn't make reference to this structure (it describes thyroid cartilage as a whole)
| id: UBERON:7770002 | ||
| name: outer cortex of thyroid cartilage | ||
| def: "The outer region of the thyroid cartilage containing denser hyaline cartilage with a higher collagen matrix density, providing structural rigidity. It serves as the attachment site for extrinsic muscles (e.g., sternothyroid, thyrohyoid) via the oblique line on the external surface." [https://geiselmed.dartmouth.edu/radiology/wp-content/uploads/sites/47/2019/04/Pitfalls-Staging-Laryngeal-SCCa-2013-Baugnon.pdf, https://www.kenhub.com/en/library/anatomy/thyroid-cartilage, https://teachmeanatomy.info/neck/viscera/larynx/laryngealcartilages/] | ||
| synonym: "outer region of thyroid cartilage" EXACT [] |
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In the kenhub page there is an exact synonym: external surface of thyroid cartilage
| [Term] | ||
| id: UBERON:7770002 | ||
| name: outer cortex of thyroid cartilage | ||
| def: "The outer region of the thyroid cartilage containing denser hyaline cartilage with a higher collagen matrix density, providing structural rigidity. It serves as the attachment site for extrinsic muscles (e.g., sternothyroid, thyrohyoid) via the oblique line on the external surface." [https://geiselmed.dartmouth.edu/radiology/wp-content/uploads/sites/47/2019/04/Pitfalls-Staging-Laryngeal-SCCa-2013-Baugnon.pdf, https://www.kenhub.com/en/library/anatomy/thyroid-cartilage, https://teachmeanatomy.info/neck/viscera/larynx/laryngealcartilages/] |
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I can't find the information in the references.
Agreed. Apologies for rushing this one and the extra work for you. Came from a quick Perplexity search using their default model. I now think it might be easier to just define in terms of the different functions/connections of each side, which do not seem controversial. |
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This PR has not seen any activity in the past month; if nobody comments or reviews it in the next week, the PR creator will be allowed to proceed with merging without explicit approval, should they wish to do so. |
Summary
This PR addresses issue #3535 and should close related issues #3459 and #3460.
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